Compositions for gastrointestinal administration of RNA

摘要

The present invention relates to a pharmaceutical composition comprising a polyribonucleotide (RNA) and a cationic agent, wherein said pharmaceutical composition is formulated as a solid dosage form for administration to the gastrointestinal (Gl) tract. The present invention furthermore relates to the use of such a pharmaceutical composition for systemic delivery of RNA and to a method for systemic delivery of RNA to a subject comprising the step of administering such a pharmaceutical composition to the Gl tract. Furthermore, the present invention relates to a kit.