BOMBESIN ANALOG PEPTIDE ANTAGONIST CONJUGATES

摘要

To provide a diagnostic and therapeutic medicament, a bombesin analog peptide antagonist conjugate is provided which has general Formula (I), wherein A is a metal chelator comprising at least one radionuclide metal, B is a spacer linked to N-terminal of C or a covalent bond and C is a bombesin analog peptide antagonist having a sequence as claimed, where further x is an integer from 1 to 3 and n is an integer from 1 to 6.
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ (I)€ƒ€ƒ€ƒ€ƒ€ƒ[A-(B) n ] x -C