| 发明名称 |
USE OF .ALPHA.-MSH AND EPO FOR PREVENTING OR TREATING ISCHEMIC CONDITIONS |
| 摘要 |
The present invention relates to a method for treating or preventing ischemi a induced organ dysfunction. The method comprises administration of an effecti ve dose of .alpha.-MSH and/or an .alpha.-MSH equivalent and EPO and/or an EPO equivalent to an individual in need thereof. Examples of ischemic conditions , which may be treated according to the present invention, are: Ischemia induc ed renal failure, myocardial ischemia, intestinal ischemia and cerebral ischemi a. In various animal models of ischemia the combination of .alpha.-MSH and rh-E PO has been shown to have a synergistic effect in reversing the adverse effects of the ischemia.
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| 申请公布号 |
CA2407785(A1) |
申请公布日期 |
2001.11.08 |
| 申请号 |
CA20012407785 |
申请日期 |
2001.05.02 |
| 申请人 |
ACTION PHARMA APS |
发明人 |
BJERKE, THORBJORN;JONASSEN, THOMAS ENGELBRECHT NORKILD;FROKLAER, JORGEN;NIELSEN, SOREN |
| 分类号 |
A61K38/22;A61K38/13;A61K38/18;A61K38/19;A61K38/20;A61K38/34;A61P1/04;A61P3/06;A61P3/10;A61P7/00;A61P7/06;A61P9/00;A61P11/02;A61P11/06;A61P17/04;A61P17/06;A61P19/02;A61P19/06;A61P19/08;A61P19/10;A61P21/00;A61P27/00;A61P27/02;A61P29/00;A61P31/04;A61P31/06;A61P31/10;A61P31/12;A61P31/18;A61P35/00;A61P35/02;A61P35/04;A61P37/02;A61P37/06;(IPC1-7):A61K38/34 |
主分类号 |
A61K38/22 |
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