发明名称 |
HUMAN POLYPEPTIDES CAUSING OR LEADING TO THE KILLING OF CELLS INCLUDING LYMPHOID TUMOR CELLS |
摘要 |
The present invention relates to polypeptide compositions which bind to cell surface epitopes and, in multivalent forms, cause or lead to the killing of cells including lymphoid tumor cells, and in the case of monovalent forms, cause immunosuppression or otherwise inhibit activation of lymphocytes. The invention further relates to nucleic acids encoding the polypeptides, methods for the production of the polypeptides, methods for killing cells, methods for immunosuppressing a patient, pharmaceutical, diagnostic and multivalent compositions and kits comprising the polypeptides and uses of the polypeptides. |
申请公布号 |
WO0187337(A1) |
申请公布日期 |
2001.11.22 |
申请号 |
WO2001US15625 |
申请日期 |
2001.05.14 |
申请人 |
GPC BIOTECH AG;MORPHOSYS AG;NAGY, ZOLTAN;BRUNNER, CHRISTOPH;TESAR, MICHAEL;THOMASSEN-WOLF, ELISABETH |
发明人 |
NAGY, ZOLTAN;BRUNNER, CHRISTOPH;TESAR, MICHAEL;THOMASSEN-WOLF, ELISABETH |
分类号 |
C12N15/09;A61K38/00;A61K39/00;A61K39/395;A61K39/44;A61P1/04;A61P1/16;A61P1/18;A61P3/10;A61P5/14;A61P13/12;A61P17/00;A61P17/06;A61P19/02;A61P21/04;A61P25/00;A61P35/02;A61P37/02;A61P37/06;A61P43/00;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/06;C12N5/10;C12P21/02;C12Q1/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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