发明名称 OPHTHALMIC NANOPARTICULATE FORMULATION OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR
摘要 <p>The present invention is directed to a novel pharmaceutical composition suitable for ophthalmic use comprising nanoparticles dispersed in a liquid dispersion medium, wherein said nanoparticles comprise a cyclooxygenase-2 selective inhibitor having adsorbed on the surface thereof at least one surface stabilizer. The ophthalmic formulation of the present invention is stable, non-irritating and sufficiently bioavailable. The invention also encompasses a process for making as well as a kit for preparing the novel ophthalmic formulation.</p>
申请公布号 WO2006062875(A1) 申请公布日期 2006.06.15
申请号 WO2005US43858 申请日期 2005.12.05
申请人 MERCK & CO., INC.;PANMAI, SANTIPHARP;ALANI, LAMAN, L. 发明人 PANMAI, SANTIPHARP;ALANI, LAMAN, L.
分类号 A61K31/415 主分类号 A61K31/415
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