发明名称 |
AUTOANTIGENS FOR IMPROVED DIAGNOSIS, PROGNOSIS AND TREATMENT OF INFLAMMATORY NEUROLOGICAL DISEASES |
摘要 |
According to the invention, autoantibodies, the appearance of which is characteristic of neurological autoimmune diseases, especially multiple sclerosis, are detected and the respective autoantigens identified. It can further be shown that many of these autoantigens are expressed specifically in the brain. The identification of the autoantigens and autoantibodies is useful for diagnosis and treatment. A brain-specific expression of the autoantigens further emphasizes an important role of the antigens and antibodies in the origin and development of neurological autoimmune diseases. |
申请公布号 |
WO2008043524(A2) |
申请公布日期 |
2008.04.17 |
申请号 |
WO2007EP08776 |
申请日期 |
2007.10.09 |
申请人 |
GANYMED PHARMACEUTICALS AG;JOHANNES GUTENBERG-UNIVERSITAET MAINZ;SAHIN, UGUR;TUERECI, OEZLEM;ZAIGLER, ALEXANDER |
发明人 |
SAHIN, UGUR;TUERECI, OEZLEM;ZAIGLER, ALEXANDER |
分类号 |
G01N33/564;G01N33/50;G01N33/569 |
主分类号 |
G01N33/564 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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