摘要 |
<p>The invention provides a method of treating neoplastic disease in a subject, said method comprising the simultaneous, sequential or separate, administration to said subject of an effective amount of (i) an inhibitor of a first EGF, e.g. HB-EGF and (ii) an inhibitor of a second EGF, e.g. AREG. Also described are novel synergistic combinations of of EGF inhibitors with topoisomerase inhibitors which attenuate tumour cell growth. Further described are novel anti AREG antibodies.</p> |
申请人 |
FUSION ANTIBODIES LIMITED;JOHNSTON, JAMES;OLWILL, SHANE;BROWN, JILL;MORGAN, NUALA;JAQUIN, THOMAS;SCOTT, CHRISTOPHER |
发明人 |
JOHNSTON, JAMES;OLWILL, SHANE;BROWN, JILL;MORGAN, NUALA;JAQUIN, THOMAS;SCOTT, CHRISTOPHER |