发明名称 AMINO ACID SEQUENCES FACILITATING PENETRATION OF A SUBSTANCEOF INTEREST INTO CELLS AND/OR CELL NUCLEI
摘要 The present invention relates to an amino acid sequence being able to facilitate penetration of a substance of interest inside cells and/or cell nuclei and having the following formula (I) [(X1)p [(X)0 (B)nX B X X B]m (X2 ) q Wherein X1 and X2 are amino acid sequences of 1 to 20 amino acids; p and q are whole numbers between 0 and 5; B is a basic amino acid; X is a non-basic , preferably hydrophobic amino acid, such as alanine, isoleucine, leucine, methionine, phenylalanine, tryptophan, valine or tyrosine; n is 2 or 3; m is 1 to 4 ; o is 0 or 1. between 0 and 5; B is a basic amino acid; X is a non- basic, preferably hydrophobic amino acid, such as alanine, isoleucine, leucine, methionine phenylalanine, tryptophan, valine or tyrosine; n is 2 or 3; m is 1 to 4; o is 0 or 1.
申请公布号 CA2535670(A1) 申请公布日期 2005.02.24
申请号 CA20042535670 申请日期 2004.08.13
申请人 DIATOS 发明人 AVRAMEAS, ALEXANDRE
分类号 C07K16/00;A61K31/70;A61K31/7048;A61K38/03;A61K38/08;A61K38/10;A61K38/16;A61K45/00;A61K45/06;A61K47/00;A61K47/48;A61K48/00;C07K14/00;C07K16/46;C07K19/00;C12N1/15;C12N5/20;C12N15/11;C12N15/85 主分类号 C07K16/00
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