发明名称 Reaction co-crystallization of molecular complexes or co-crystals
摘要 Multi-component crystals (co-crystals) are prepared by combining co-crystal components in non-stoichiometric concentrations in solution. The solubility of the molecular complex in the solvent is reduced, increasing the probability that the molecular complex is the least soluble form in the system, upon which it precipitates. A crystalline product is produced without the need for grinding, solvent evaporation, or temperature variation.
申请公布号 US2007099237(A1) 申请公布日期 2007.05.03
申请号 US20050262995 申请日期 2005.10.31
申请人 THE REGENTS OF THE UNIVERSITY OF MICHIGAN 发明人 RODRIGUEZ-HORNEDO NAIR
分类号 C40B40/04;A61K31/192;A61K31/496;A61K31/522;A61K31/55;A61K31/655 主分类号 C40B40/04
代理机构 代理人
主权项
地址