发明名称 |
MONITOR FOR PARTICLE INJECTOR |
摘要 |
Approaches for determining the delivery success of a particle, such as a drug particle, are disclosed. A system for monitoring delivery of particles to biological tissue includes a volume, an optical component, a detector, and an analyzer. The volume comprises a space through which a particle can pass in a desired direction. The optical component is configured to provide a measurement light. The detector is positioned to detect light emanating from the particle in response to the measurement light. The detected light is modulated as the particle moves along a detection axis. The detector is configured to generate a time-varying signal in response to the detected light. The analyzer is configured to receive the time-varying signal and determine a delivery success of the particle into a biological tissue based upon characteristics of the time-varying signal. |
申请公布号 |
US2016317747(A1) |
申请公布日期 |
2016.11.03 |
申请号 |
US201615209450 |
申请日期 |
2016.07.13 |
申请人 |
Palo Alto Research Center Incorporated |
发明人 |
Kiesel Peter;Martini Joerg;Chow Eugene M.;Uhland Scott;Johnson Noble M. |
分类号 |
A61M5/30;G01N15/14;G01B11/14 |
主分类号 |
A61M5/30 |
代理机构 |
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代理人 |
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主权项 |
1. An assembly for delivering and monitoring delivery of particles to a material, comprising:
a delivery device configured to contain a particle and accelerate the particle in a desired direction and across an interface into the material; a volume through which the particle can pass; a spatial filter having mask features; a detector positioned to detect light emanating from the particle along a detection region within the volume, the detected light is modulated according to the mask features as the particle moves along the detection region, the detector configured to generate a time-varying signal in response to the detected light; and an analyzer configured to receive the time-varying signal and determine a delivery success of the particle into the material based upon characteristics of the time-varying signal. |
地址 |
Palo Alto CA US |