发明名称 SIRT 1 ACTIVATOR INCLUDING SYRINGARESINOL
摘要 The present invention relates to a compound of Formula 1, and an SIRT 1 activator including, as an active ingredient, derivatives thereof or pharmaceutically acceptable salts thereof. The present invention also relates to a composition including the SIRT 1 activator for detoxification, for the improvement of metabolic disorders, for the prevention or improvement of eye diseases, or the prevention or improvement of immune diseases.
申请公布号 US2016263079(A1) 申请公布日期 2016.09.15
申请号 US201615160239 申请日期 2016.05.20
申请人 AMOREPACIFIC CORPORATION 发明人 KIM Byung Gyu;JEONG Hyun Woo;KIM Su Kyung;CHO Si Young;PARK Chan Woong;SEO Dae Bang;KIM Wan Gi;LEE Sang Jun
分类号 A61K31/34;A23L2/52;A61K36/258 主分类号 A61K31/34
代理机构 代理人
主权项 1. A method of treating an eye disease in a subject suffering from the eye disease comprising administering an effective amount of a compound of Chemical Formula 1, or a pharmaceutically acceptable salt thereof to the subject: wherein R1, R2, R3 or R4 are independently an unbranched or branched C1-C18 alkyl group, C1-C18 alkoxy group, C1-C18 alkenyl group, C1-C18 alkynyl group or C3-C6 cyclic alkyl group, and R5, R6, R7, R8, R9, R10 or R11 are independently hydrogen or an unbranched or branched C1-C18 alkyl group, C1-C18 alkoxy group, C1-C18 alkenyl group, C1-C18 alkynyl group or C3-C6 cyclic alkyl group, and wherein the compound of Chemical Formula 1 treats the eye disease in the subject.
地址 Seoul KR