摘要 |
The present invention is concerned among others with compounds of formula (1), the N-oxides, the pharmaceutically acceptable addition salts, the quaternary amines and stereochemically isomeric forms thereof, wherein Q is halo, C1-6 alkyl or C2-6 alkenyl; X is (a-2) with q and r being O and Z being O, S or SO; R1 is aryl; R2 is selected from formyl; C1-6alkyloxycarbonylalkyl; Het<2>; Het<2>C1-6alkyl, C1-6alkylthio; C1-6alkyl optionally substituted with one or two substituents each independently selected from hydroxy, and halo; R3 is selected from formyl; C1-6alkyl optionally substituted with one or two C1-6alkyloxy; R4 is hydrogen, with HIV inhibiting properties.
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申请人 |
JANSSEN PHARMACEUTICA N.V.;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;INSTITUT CURIE;GUILLEMONT, JEROME;BENJAHAD, ABDELLAH;MABIRE, DOMINIQUE;N'GUYEN, CHI, HUNG;GRIERSON, DAVID;MONNERET, CLAUDE;BISAGNI, EMILE;SANZ, GERARD;DECRANE, LAURENCE |
发明人 |
GUILLEMONT, JEROME;BENJAHAD, ABDELLAH;MABIRE, DOMINIQUE;N'GUYEN, CHI, HUNG;GRIERSON, DAVID;MONNERET, CLAUDE;BISAGNI, EMILE;SANZ, GERARD;DECRANE, LAURENCE |