发明名称 |
RANDOM COPOLYMER THERAPEUTIC AGENT CARRIERS AND ASSEMBLIES THEREOF |
摘要 |
Provided herein are particles assemblies including a shell surrounding a core. The shell includes a particle-stabilizing random copolymer. The core includes a core random copolymer. The particle assemblies have a biomimetic design in which the polymeric components containing discrete chemical and biological functionalities are designed to spontaneously self-assemble into particles. Also provided herein are random copolymers having conjugated therapeutic agents that can be cleaved from the copolymers by an enzyme or water. |
申请公布号 |
US2016279251(A1) |
申请公布日期 |
2016.09.29 |
申请号 |
US201415035721 |
申请日期 |
2014.11.12 |
申请人 |
UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION |
发明人 |
Stayton Patrick S.;Convertine Anthony;Ratner Daniel M.;Srinivasan Selvi;Das Debobrato;Su Fang-Yi;Chen Jasmin;Chiu David Yee-Shawn;Lane Daniel Douglas |
分类号 |
A61K47/48;A61K31/407;A61K31/4745;A61K31/7036;A61K31/337;A61K31/496 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Seattle WA US |