| 发明名称 |
ANTI-CDH3 ANTIBODY HAVING HIGH INTERNALIZATION CAPACITY |
| 摘要 |
PROBLEM TO BE SOLVED: To provide an anti-cadherin antibody having a high internalization capacity and provide an anti-cadherin antibody-drug conjugate that effectively kills cadherin-expressing cancer cells with the use of such antibody.SOLUTION: The present invention provides an anti-cadherin antibody which recognizes a cadherin domain 1 (EC1) of cadherin and exhibits a high internalization capacity.SELECTED DRAWING: None |
| 申请公布号 |
JP2016175945(A) |
申请公布日期 |
2016.10.06 |
| 申请号 |
JP20160127379 |
申请日期 |
2016.06.28 |
| 申请人 |
PERSEUS PROTEOMICS INC |
发明人 |
ISHII KEISUKE;KATSUMI KEIKO;MATSUURA TADASHI;SUDO YUKIO;MITOMO KATSUYUKI;KODA KATSUSHI |
| 分类号 |
C07K16/28;A61K31/537;A61K38/00;A61K39/395;A61K45/00;A61K51/00;A61P35/00 |
主分类号 |
C07K16/28 |
| 代理机构 |
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代理人 |
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