NOVEL SUBSTITUTED 7-DEAZAPURINE RIBONUCLEOSIDES FOR THERAPEUTIC USES

摘要

Compounds of Formula I and a pharmaceutically acceptable salt thereof, an optical isomer thereof, or a mixture of optical isomers thereof, as well as compositions which include such compounds and therapeutic methods that utilize such compounds and/or compositions.

主权项

1. A compound of formula I: wherein, R is methylsulfanyl, methoxy, methylamino, dimethylamino or methyl; R′ is furan-2-yl, furan-3-yl, thiophen-2-yl, thiophen-3-yl, phenyl, benzofuran-2-yl, ethynyl, or iodine; a pharmaceutically acceptable salt thereof, an optical isomer thereof, or a mixture of optical isomers thereof; with the proviso that if R′ is iodine, R is not methoxy.