Provided is a single-stranded nucleic acid molecule represented by formula (I): 5'-uagcaccauuugaaaucaguguucc-P-ggaacacugauuucaaauggugcuauu-3' (SEQ ID NO: 1) (in the formula, -P- indicates a proline-derivative linker represented by formula (Ia)). Further provided is a therapeutic agent for corneal diseases such as ocular surface disease, said therapeutic agent having the single-stranded nucleic acid molecule as an active ingredient.
申请公布号
WO2016167366(A1)
申请公布日期
2016.10.20
申请号
WO2016JP62183
申请日期
2016.04.15
申请人
THE UNIVERSITY OF TOKYO;TOKYO MEDICAL UNIVERSITY;TAKEUCHI, Hirofumi;BONAC CORPORATION