METHODS, SYSTEMS AND COMPUTER PROGRAM FOR 3D-REGISTRATION OF THREE DIMENSIONAL DATA SETS OBTAINED BY PREFERABLY OPTICAL COHERENCE TOMOGRAPHY BASED ON THE ALIGNMENT OF PROJECTION IMAGES OR FUNDUS IMAGES, RESPECTIVELY

摘要

Methods of analyzing three dimensional data sets obtained from a sample over time are provided. A first three dimensional data set is obtained from the sample at a first time. A first volume intensity projection (VIP) image is created from the first three dimensional data set. One or more first landmarks are identified and registered in the first VIP image. A second three dimensional data set is obtained from the sample at a second time, different from the first time. A second VIP image is created from the second three dimensional data set. The one ore more first landmarks are identified and registered in the second VIP image. The first and second VIP images are aligned based on the registered one or more first landmarks in the first and second VIP images. Related systems and computer program products are also provided.