发明名称 DOSAGE OF OLIGONUCLEOTIDES
摘要 Use of at least one oligonucleotide with a length of from 8 to 30 nucleotide building blocks for manufacturing a pharmaceutical preparation for the prophylaxis and/or the treatment of diseases, that are modulated by TGF-beta1, TGF-beta3, VEGF, interleukin-10, c-jun, c-fos, and/or prostaglandin E2 in a mammal, wherein said oligonucleotide hybridizes with a messenger RNA of a TGF-beta1, TGF-beta3, VEGF, interleukin-10, c-jun, c-fos and/or prostaglandin E2 gene and wherein said preparation comprises said oligonucleotide in a concentration of about 1 microM to about 25 microM.
申请公布号 ZA200809354(B) 申请公布日期 2010.02.24
申请号 ZA20080009354 申请日期 2008.10.31
申请人 ANTISENSE PHARMA GMBH 发明人 SCHLINGENSIEPEN KARL HERMANN;SCHLINGENSIEPEN REIMAR
分类号 A61K;A61P;C12N15/11;C12N15/113 主分类号 A61K
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