发明名称 |
BIOSENSOR BASED ON A TETHERED PARTICLE |
摘要 |
A method for sensing an analyte uses tethered particle motion. A functionalized particle [500] has a first state [504] in which the functionalized particle is bound to the surface and a second state [502] in which the functionalized particle is not bound to the surface, where the functionalized particle switches between the first and second states depending on the presence and absence of the analyte, thereby changing motion characteristics of the functionalized particle depending on the presence of the analyte. A spatial coordinate parameter of the functionalized particle is measured by a detector [516], and a processor [518] determines the presence/concentration of the analyte from changes in the measured spatial coordinate parameter. |
申请公布号 |
WO2016096901(A1) |
申请公布日期 |
2016.06.23 |
申请号 |
WO2015EP79864 |
申请日期 |
2015.12.15 |
申请人 |
TECHNISCHE UNIVERSITEIT EINDHOVEN |
发明人 |
PRINS, MENNO WILLEM JOSÉ;MERKX, MAARTEN;IJZENDOORN, LEONARDUS JOSEPHUS;ZIJLSTRA, PETER;VISSER, EMILIUS WILLEM ADRIAAN;SCHEEPERS, MAX ROSE-MARIE WILHELMUS |
分类号 |
G01N33/542;C12Q1/68;G01N33/543 |
主分类号 |
G01N33/542 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|