发明名称 BENZIMIDAZOLE AND IMADAZOPYRIDINE CARBOXIMIDAMIDE COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE
摘要 The present disclosure provides indoleamine 2,3 -dioxygenase 1 (IDO1) inhibitors of Formula I: or pharmaceutically acceptable salts thereof, in which X, L, n, m, R1, R2a, R2b, Rn, Rm, and R1 are as defined herein, as well as pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts thereof, and methods of using the same to treat conditions mediated by IDO1.
申请公布号 WO2016186967(A1) 申请公布日期 2016.11.24
申请号 WO2016US32152 申请日期 2016.05.12
申请人 GILEAD SCIENCES, INC. 发明人 BARTLETT, Mark, J.;CODELLI, Julian, Andrew;CORKEY, Britton, Kenneth;COSMAN, Jennifer, Leigh;ELBEL, Kristyna;LOYER-DREW, Jennifer, Alissa;SPERANDIO, David;VAN VELDHUIZEN, Joshua;YANG, Hai;YEUNG, Suet, Chung
分类号 C07D403/12;A61K31/4184;A61K31/4188;A61K31/506;A61K31/5377;A61K31/553;A61P25/28;A61P31/12;A61P35/00;A61P37/02;C07D235/16;C07D235/24;C07D401/04;C07D401/12;C07D405/12;C07D405/14;C07D409/12;C07D413/12;C07D471/04;C07D487/04 主分类号 C07D403/12
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