发明名称 |
BENZIMIDAZOLE AND IMADAZOPYRIDINE CARBOXIMIDAMIDE COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE |
摘要 |
The present disclosure provides indoleamine 2,3 -dioxygenase 1 (IDO1) inhibitors of Formula I: or pharmaceutically acceptable salts thereof, in which X, L, n, m, R1, R2a, R2b, Rn, Rm, and R1 are as defined herein, as well as pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts thereof, and methods of using the same to treat conditions mediated by IDO1. |
申请公布号 |
WO2016186967(A1) |
申请公布日期 |
2016.11.24 |
申请号 |
WO2016US32152 |
申请日期 |
2016.05.12 |
申请人 |
GILEAD SCIENCES, INC. |
发明人 |
BARTLETT, Mark, J.;CODELLI, Julian, Andrew;CORKEY, Britton, Kenneth;COSMAN, Jennifer, Leigh;ELBEL, Kristyna;LOYER-DREW, Jennifer, Alissa;SPERANDIO, David;VAN VELDHUIZEN, Joshua;YANG, Hai;YEUNG, Suet, Chung |
分类号 |
C07D403/12;A61K31/4184;A61K31/4188;A61K31/506;A61K31/5377;A61K31/553;A61P25/28;A61P31/12;A61P35/00;A61P37/02;C07D235/16;C07D235/24;C07D401/04;C07D401/12;C07D405/12;C07D405/14;C07D409/12;C07D413/12;C07D471/04;C07D487/04 |
主分类号 |
C07D403/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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