Method for the preparation of phenols

摘要

The present invention relates to a method for the preparation of phenols, in which an aryldiazonium salt, which is prepared by the diazotisation of a corresponding aromatic, primary amine, is decomposed by heating in a mixture containing hot water, a mineral acid and an organic solvent, wherein the organic solvent contains a ketone of formula (I) R1C(O)R2 ;
in which R1 and R2 independently stand for (C1-C5)-alkyl and R1 and R2 together have at least four carbon atoms, wherein the aromatic primary amine is aniline or a substituted aniline, which contains at least one further substituent which is selected from: alkyl, alkenyl, alkynyl, halogen, haloalkyl, cycloalkyl, heteroaryl, carboxyl, cyan, alkoxyl and ester, and wherein substantially no copper salts are contained in the mixture.

主权项

1. A method for the preparation of phenols in which an aryldiazonium salt, which is prepared by the diazotisation of a corresponding aromatic primary amine, is decomposed by heating in a mixture containing hot water, a mineral acid and an organic solvent, wherein,
the organic solvent contains a ketone of formula (I) R1C(O)R2 in which R1 and R2 independently stand for (C1- C5)-alkyl and R1 and R2 together have at least four carbon atoms, wherein the aromatic primary amine is aniline or a substituted aniline which contains at least one further substituent which is selected from the group consisting of alkyl, alkenyl, alkynyl, halogen, haloalkyl, cycloalkyl, heteroaryl, carboxyl, cyanide, alkoxyl and ester, and wherein substantially no copper salts are contained in the mixture containing hot water, a mineral acid and an organic solvent.