摘要 |
<P>PROBLEM TO BE SOLVED: To provide a STAT-6 (signal transducer and activator of transcription 6) activation inhibitor that exactly inhibits STAT-6 activation. <P>SOLUTION: The STAT-6 activation inhibitor comprises a 4-cyclohexyldihydropyrimidin-2-one derivative represented by general formula (1) [wherein, R<SP>1</SP>and R<SP>2</SP>are each the same or different a 1-6C alkyl, 2-6C alkenyl or 2-6C acyl (wherein, the substituent(s) thereof may be further substituted with one 6-10C aryl, 6-10C aryloxy or 6-10C arylcarbonyl)] or a solvate thereof. <P>COPYRIGHT: (C)2008,JPO&INPIT |