发明名称 NEW 4-CYCLOHEXYLDIHYDROPYRIMIDIN-2-ONE DERIVATIVE AND STAT-6 ACTIVATION INHIBITOR COMPRISING THE SAME
摘要 <P>PROBLEM TO BE SOLVED: To provide a STAT-6 (signal transducer and activator of transcription 6) activation inhibitor that exactly inhibits STAT-6 activation. <P>SOLUTION: The STAT-6 activation inhibitor comprises a 4-cyclohexyldihydropyrimidin-2-one derivative represented by general formula (1) [wherein, R<SP>1</SP>and R<SP>2</SP>are each the same or different a 1-6C alkyl, 2-6C alkenyl or 2-6C acyl (wherein, the substituent(s) thereof may be further substituted with one 6-10C aryl, 6-10C aryloxy or 6-10C arylcarbonyl)] or a solvate thereof. <P>COPYRIGHT: (C)2008,JPO&INPIT
申请公布号 JP2008208103(A) 申请公布日期 2008.09.11
申请号 JP20070048548 申请日期 2007.02.28
申请人 KOWA CO 发明人 KITAMURA TAKAHIRO;ARAI TOSHIHARU;DOI TAKESHI;SUDA MAKOTO;MORIKAWA SHIGERU;TAKIZAWA TOSHIAKI
分类号 C07D239/36;A61K31/513;A61P11/00;A61P11/06;A61P17/00;A61P27/02;A61P27/16;A61P29/00;A61P37/08;C12N15/09 主分类号 C07D239/36
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