NOVEL PYRIDO[2,3-B]PYRAZINONES AS BET-FAMILY BROMODOMAIN INHIBITORS

摘要

Disclosed are novel pyrido[2,3-b]pyrazinones of formulae (I) and (II) or pharmaceutically acceptable salts thereof. Pharmaceutical compositions and the use of the compounds to treat diseases or disorders that are BET family bromodomain-dependent, e.g. cancer, are also disclosed. Methods for preparing and using these compounds are further described.