发明名称 CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT
摘要 Novel cromolyn analogs useful as imaging agents for detecting atherosclerotic plaques and for treating atherosclerosis and Alzheimer's Disease, and methods of making the cromolyn analogs, are disclosed. The cromolyn analogs have the general formula;;;wherein X is OH, C1-C6 alkoxyl; Y and Z are independently selected from a C1-C6 alkyl, C1-C6 alkoxyl, halogen, mi-substituted or C1-C6 substituted amine, 18F, 19F, or H; and n is 1, 2, or 3; and wherein for structure (I), if n are both 1 and Y and Z are both H and X is OH.
申请公布号 US2016263257(A1) 申请公布日期 2016.09.15
申请号 US201415031098 申请日期 2014.10.22
申请人 ELMALEH David R.;SHOUP Timothy 发明人 Elmaleh David R.;Shoup Timothy M.
分类号 A61K51/04;A61K31/352;A61K31/192;A61K9/48;A61K9/00 主分类号 A61K51/04
代理机构 代理人
主权项
地址 Newton MA US