The present invention provides an isolated antibody that specifically binds to HPA- a. Also provided is a nucleic acid molecule that encodes the antibody, and compositions comprising the antibody. Also provided is a method of producing the antibody and methods and uses which employ the antibody. Also provided are therapeutic uses of the antibody, for example in the treatment or prophylaxis of fetal and neonatal alloimmune thrombocytopenia (FNAIT).
申请公布号
AU2015239606(A1)
申请公布日期
2016.10.20
申请号
AU20150239606
申请日期
2015.03.31
申请人
Universitetet i Tromso - Norges Arktiske Universitet;Norinnova Technology Transfer AS;University Hospital of North Norway
发明人
Stuge, Tor Brynjar;Husebekk, Anne;Tiller, Heidi;Eksteen, Mariana;Skogen, Bjorn Ragnar;Ihle, Oistein;Michaelsen, Terje