ABUSE-DETERRENT OPIOIDS

摘要

Described herein are abuse deterrent controlled release oral pharmaceutical compositions comprising and methods for making the same. In particular, an abuse deterrent controlled release oral pharmaceutical composition comprising a soft capsule and an abuse deterrent controlled release matrix comprising an active pharmaceutical ingredient are described.

主权项

1. An abuse deterrent oral pharmaceutical composition comprising a tamper resistant controlled release matrix comprising:
(a) at least one lipid or lipophilic vehicle; (b) at least one organogelator; (c) at least one hydrophilic polymer; (d) at least one hydrophilic vehicle; and (e) at least one active pharmaceutical ingredient;wherein the matrix is resistant to tampering and is encapsulated in a soft capsule shell.