| 发明名称 |
CELL PERMEABLE ATP ANALOG FOR KINASE-CATALYZED BIOTINYLATION |
| 摘要 |
A cell permeable ATP analog has the following formula:;;or a physiologically acceptable salt thereof,
wherein:
R0 is
;;n, o, p are each independently 1, 2, 3, 4, 5, or 6, m is 0, 1, 2, 3, 4, or 5; X is O, S, NH, or CH2. R1 is H or C1-6 alkyl, R2 is H, C1-6 alkyl, C6-30 aryl, C5-32 heteroaryl, or C7-32 alkylaryl; R3, R4 are each independently H, C1-6 alkyl, C6-30 aryl, C5-32 heteroaryl, or C7-32 alkylaryl, wherein R3, and R4 can be combined together to form a ring structure. |
| 申请公布号 |
US2016377626(A1) |
申请公布日期 |
2016.12.29 |
| 申请号 |
US201615187206 |
申请日期 |
2016.06.20 |
| 申请人 |
WAYNE STATE UNIVERSITY |
发明人 |
PFLUM MARY KAY |
| 分类号 |
G01N33/58;C08B37/08;G01N33/82;C07H19/20 |
主分类号 |
G01N33/58 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A cell permeable ATP analog having the following formula: or a physiologically or pharmaceutically acceptable salt thereof, wherein: R0 is n, o, p are each independently 1, 2, 3, 4, 5, or 6; m is 0, 1, 2, 3, 4, or 5; X is O, S, NH, or CH2; R1 is H or C1-6 alkyl, R2 is H, C1-6 alkyl, C6-30 aryl, C5-32 heteroaryl, or C7-32 alkylaryl; and R3, R4 are each independently H, C1-6 alkyl, C6-30 aryl, C5-32 heteroaryl, or C7-32 alkylaryl, wherein R3, and R4 can be combined together to form a ring structure. |
| 地址 |
Detroit MI US |
