发明名称 |
SPECIFIC DELIVERY OF TOXINS CONJUGATED WTIH ANTIBODIES TO ACTIVATED MATRIPTASE |
摘要 |
Disclosed are antibody drug conjugates (ADC) that include highly potent toxic agents with specific antibodies to target tumors. Also disclosed are related antibodies, polypeptides, nucleic acids, host cells, compositions, and uses. |
申请公布号 |
EP2904015(A4) |
申请公布日期 |
2016.10.05 |
申请号 |
EP20130844164 |
申请日期 |
2013.10.02 |
申请人 |
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY;GEORGETOWN UNIVERSITY |
发明人 |
LIN, SIANG-YO;BERTINO, JOSEPH R.;LIN, CHEN-YONG;JOHNSON, MICHAEL |
分类号 |
C07K16/40;A61K39/00;A61K47/48;A61P35/00;C07K19/00 |
主分类号 |
C07K16/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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