| 发明名称 |
METHODS FOR MODULATING EXPRESSION OF C9ORF72 ANTISENSE TRANSCRIPT |
| 摘要 |
Disclosed herein are methods for reducing expression of C90RF72 antisense transcript in an animal with C90RF72 antisense transcript specific inhibitors. Such methods are useful to treat, prevent, or ameliorate neurodegenerative diseases in an individual in need thereof. Such C90RF72 antisense transcript specific inhibitors include antisense compounds. |
| 申请公布号 |
US2016237432(A1) |
申请公布日期 |
2016.08.18 |
| 申请号 |
US201415029210 |
申请日期 |
2014.10.14 |
| 申请人 |
OINIS PHARMACEUTICALS, INC. ;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ;LUDWING INSTITUTE FOR CANCER RESEARCH |
发明人 |
Bennett C. Frank;Rigo Frank;Cleveland Don W.;Lagier-Tourenne Clotilde;Ravits John M.;Baughn Michael W. |
| 分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method, comprising contacting a cell with a C9ORF72 antisense transcript specific inhibitor. |
| 地址 |
Carlsbad CA US |
