| 摘要 |
Y receptor agonists selected from
[Lys4,Leu17,Gln34]PP,
[Cys2, D-Cys27]PYY2-36,
Lys4,Leu17,Leu30,Gln34]PP
[Lys4,Nle17,Nle30,Gln34]PP
[Lys4,Gln34]PP
[Cys2,D-Cys27]PYY
[Cys2,D-Cys27]NPY
[Cys2,Ile3,D-Cys27,Val31]NPY
[Cys2,Ile3,D-Cys27,Leu28,Val31]NPY
[Cys2,Ile3,Nle17,D-Cys27,Nle28,Val31]NPY
and N-acylated and conservatively substituted analogues thereof. are selective for the Y2 receptor over the Y1 and Y4 receptors, and their use in the treatment of conditions responsive to activation of Y2 receptors, are disclosed. |
