| 发明名称 |
METHODS AND COMPOSITIONS RELATING TO CANCER THERAPY WITH DNA DAMAGING AGENTS |
| 摘要 |
Methods and compositions are provided for predicting efficacy of a DNA damaging agent in a cancer patient or treating a cancer patient with a DNA damaging agent after evaluating efficacy. In some embodiments, an algorithm is used to evaluate efficacy and treatment. |
| 申请公布号 |
US2016369353(A1) |
申请公布日期 |
2016.12.22 |
| 申请号 |
US201615078810 |
申请日期 |
2016.03.23 |
| 申请人 |
THE UNIVERSITY OF CHICAGO |
发明人 |
Pitroda Sean P.;Weichselbaum Ralph R.;Connell Philip P. |
| 分类号 |
C12Q1/68;G06F19/24 |
主分类号 |
C12Q1/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treating a human patient with cancer comprising treating the patient with a DNA damaging agent after the patient has been determined to be a patient with predicted sensitivity to treatment with the DNA damaging agent, wherein the determination is made based on measuring the level of expression of one or more human genes involved in the repair of double-stranded DNA breaks from a biological sample from the patient. |
| 地址 |
Chicago IL US |
