FORMULATION FOR RETINOID-CONTAINING SOFT GELATIN CAPSULES

摘要

A new pharmaceutical formulation for retinoid-containing soft gelatin capsules is disclosed. The new formulation comprises a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides. Optionally, the new formulation also comprises a natural wax. In a particularly preferred embodiment, the soft gelatin capsule comprises pig gelatin in the capsule shell in combination with the above fill mass.

主权项

1. A pharmaceutical formulation for retinoids comprising a soft gelatin capsule filled with a fill mass comprising 9-cis retinoic acid or a pharmaceutically acceptable salt thereof, a natural vegetable oil, a partially hydrogenated natural vegetable oil, a medium chain triglyceride, and a natural wax, optionally further an antioxidant, and other pharmaceutically acceptable additives.