发明名称 |
Immunogenic Compositions and Vaccines Derived From Bacterial Surface Receptor Proteins |
摘要 |
The disclosure provides immunogenic compositions comprising a polypeptide comprising a C-lobe domain or an N-lobe domain of a HIBP surface receptor protein obtainable from or obtained from a Gram-negative bacterial species. The HIBP surface receptor proteins have been modified in such a manner that they are unable to bind host iron binding protein. Methods of making and using these immunogenic positions to prepare animal and human vaccines are also provided. |
申请公布号 |
US2016303217(A1) |
申请公布日期 |
2016.10.20 |
申请号 |
US201415100867 |
申请日期 |
2014.12.01 |
申请人 |
SCHRYVERS Anthony B.;MORAES Trevor F.;GRAY-OWEN Scott |
发明人 |
Schryvers Anthony B.;Moraes Trevor F.;Gray-Owen Scott |
分类号 |
A61K39/104;A61K39/095;A61K39/102 |
主分类号 |
A61K39/104 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Calgary CA |