| 发明名称 |
COMBINATION THERAPY FOR TREATING CANCER |
| 摘要 |
The present invention relates to compositions comprising inhibitors of human histone methyltransferase EZH2 and one or more other therapeutic agents, particularly anticancer agents such as prednisone, and methods of combination therapy for administering to subjects in need thereof for the treatment of cancer. |
| 申请公布号 |
US2016303135(A1) |
申请公布日期 |
2016.10.20 |
| 申请号 |
US201415101577 |
申请日期 |
2014.12.08 |
| 申请人 |
Epizyme, Inc. |
发明人 |
Keilhack Heike;Knutson Sarah K.;Kuntz Kevin W. |
| 分类号 |
A61K31/5377;A61K31/573;A61K31/404;A61K31/519;C07K16/28;A61K31/436;A61K31/675;A61K31/4375;A61K31/69;A61K39/395;A61K31/635;A61K31/52 |
主分类号 |
A61K31/5377 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treating cancer in a patient in need thereof comprising administering (i) a therapeutically effective amount of an EZH2 inhibitor and a therapeutically effective amount of a standard of care agent, (ii) a therapeutically effective amount of a combination comprising an EZH2 inhibitor and a standard of care agent, or (iii) a therapeutically effective amount of a composition comprising an EZH2 inhibitor and a standard of care agent. |
| 地址 |
Cambridge MA US |
