主权项 |
1. A method of treating a disease selected from the group consisting of cancer, Duchenne muscular dystrophy, AIDS, and progeria, comprising:
administering to a patient in need thereof an effective quantity of at least one compound of formula (IV) or a pharmaceutically acceptable salt thereof:where:
X2 represents a nitrogen atom or a CR16 group; R16 is a hydrogen atom or a group selected from: X1 represents:
a nitrogen atom,a NR11 group, ora CR10 group; R10 represents:
a hydrogen atom,an NR11R12, oran OR11 group; R11 and R12 independently represent a hydrogen atom or a C1 to C3 alkyl group; R1 represents:
a hydrogen atom,an NR11R12, oran OR12 group,with X1 representing a CH group when R1 represents an NR11R12 or an OR12 group;A represents: R4 represents:
a hydrogen atom,a C1 to C3 alkyl group, ora C(═O)NR14R15 group,with R4 representing a hydrogen atom or a C1 to C3 alkyl group when R5 or R6 is not a hydrogen atom; R5 represents:
a hydrogen atom,a C(═O)NR14R15 group, or with R5 representing a hydrogen atom when R4 or R6 is different than a hydrogen atom; R6 represents:
a hydrogen atom,a C(═O)NR14R15 group, orgroup,
with R6 representing a hydrogen atom when R5 is not a hydrogen atom or when R4 is not a hydrogen atom or a C1 to C3 alkyl group; R7 represents:
a hydrogen atom,an NR11R12, oran OR12 group,with X2 representing a CH group when R7 represents an NR11R12 or an OR12 group; R14 and R15 independently represent:
a hydrogen atom, ora linear or branched, substituted or unsubstituted C1 to C10 alkyl group, wherein one or more carbon atoms can be substituted by a nitrogen atom; and R21 and R22 independently represent a hydrogen atom or a methyl group; |