发明名称 |
AMINODIHYDROTHIAZINE DERIVATIVES SUBSTITUTED WITH CYCLIC GROUPS |
摘要 |
<p>This invention provides a compound of the formula (I):
wherein the ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; R 1 is optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl; R 2a and R 2b are each independently hydrogen, optionally substituted lower alkyl or optionally substituted acyl; R 3a , R 3b , R 3c and R 3d are each independently hydrogen, halogen, hydroxy or optionally substituted lower alkyl etc.; a pharmaceutically acceptable salt or solvate thereof,
which is useful for treating diseases induced by production, secretion and/or deposition of amyloid ² protein.</p> |
申请公布号 |
EP2147914(A1) |
申请公布日期 |
2010.01.27 |
申请号 |
EP20080751985 |
申请日期 |
2008.04.23 |
申请人 |
SHIONOGI&CO., LTD. |
发明人 |
TAMURA, YUUSUKE;SUZUKI, SHINJI;TADA, YUKIO;YONEZAWA, SHUJI;FUJIKOSHI, CHIAKI;MATSUMOTO, SAE;KOORIYAMA, YUUJI;UENO, TATSUHIKO |
分类号 |
C07D279/06;A61K31/497;A61K31/54;A61K31/541;A61P25/28;A61P43/00;C07D417/12;C07D417/14;C07D471/04;C07D487/04;C07D495/04;C07D513/04 |
主分类号 |
C07D279/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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