发明名称 |
USE OF CABAZITAXEL IN THE TREATMENT OF PROSTATE CANCER |
摘要 |
The present invention relates to cabazitaxel for use in a method for treating an AR-V7 -positive patient suffering from prostate cancer comprising determining the AR-V7-status in said patient and administering cabazitaxel. The invention also relates to a method of identifying patients with prostate cancer, eligible for treatment with cabazitaxel comprising testing a biological sample from the patient for the presence of AR-V7 circulating tumor cells, wherein the patient is eligible for treatment with said cabazitaxel if circulating tumor cells in said sample test positive for AR-V7. The invention further relates to a kit of parts for determining the AR-V7-status in isolated tumor cells of a patient with prostate cancer. |
申请公布号 |
WO2016133387(A1) |
申请公布日期 |
2016.08.25 |
申请号 |
WO2016NL50111 |
申请日期 |
2016.02.17 |
申请人 |
ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM |
发明人 |
SLEIJFER, Stefan;ONSTENK, Wendy;SIEUWERTS, Anita Maria |
分类号 |
A61K31/337;A61K31/573;A61P35/00 |
主分类号 |
A61K31/337 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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