HYBRID HOLLOW MICROCAPSULE, SCAFFOLD FOR SOFT TISSUE INCLUDING SAME, AND METHODS OF PREPARING SAME

摘要

Disclosed is a method of preparing a hollow microcapsule using freezing of macroporous materials including a crosslinked inorganic particle network capable of elastically recovering from a highly compressed deformation state, and use of the same as a scaffold for soft tissue engineering and as a drug delivery system.

主权项

1. A hollow microcapsule, comprising:
(a) a hollow core polymer layer, and (b) an organic-inorganic complex layer comprising inorganic nanoparticles and a polymer for coating capsules on the surface of the hollow core polymer layer, wherein the organic-inorganic complex layer is a single organic-inorganic complex layer or a plurality of organic-inorganic complex layers formed in a layer-by-layer manner, and the core polymer layer and the polymer for coating capsules are crosslinked.