| 发明名称 |
LIPOSOMAL CURCUMIN FOR TREATMENT OF CANCER |
| 摘要 |
The present invention provides a compositions and methods for the treatment of cancer, including pancreatic cancer, breast cancer and melanoma, in a human patient. The methods and compositions of the present invention employ curcumin or a curcumin analogue encapsulated in a colloidal drug delivery system, preferably a liposomal drug delivery system. Suitable colloidal drug delivery systems also include nanoparticles, nanocapsules, microparticles or block copolymer micelles. The colloidal drug delivery system encapsulating curcumin or a curcumin analogue is administered parenterally in a pharmaceutically acceptable carrier. |
| 申请公布号 |
US2016193159(A1) |
申请公布日期 |
2016.07.07 |
| 申请号 |
US201615069413 |
申请日期 |
2016.03.14 |
| 申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
Kurzrock Razelle;Li Lan;Mehta Kapil;Aggarwal Bharat |
| 分类号 |
A61K31/12;A61K9/127 |
主分类号 |
A61K31/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for the treatment or prevention of cancer in a mammalian subject, comprising:
a) formulation of a colloidal drug delivery system encapsulating curcumin, a curcumin analogue or a curcumin metabolite; and b) parenteral administration of the colloidal drug delivery system to a mammalian subject in a pharmaceutically acceptable carrier. |
| 地址 |
Austin TX US |
