摘要 |
FIELD: pharmaceutics.SUBSTANCE: present invention relates to FTD- and TPI-containing oral pharmaceutical composition which can be orally administered and is stable even under high humidity conditions. Oral pharmaceutical composition contains α,α,α-trifluorothymidine and 5-chloro-6-(2-iminopyrrolidine-1-yl)methyl-2,4(1H,3H)-pyrimidine dione hydrochloride as the active ingredient, and contains, as an excipient, an additive having an 85 % or greater critical relative humidity at 25 °C.EFFECT: can be orally administered and is stable even under high humidity conditions.10 cl, 17 ex, 6 tbl |