| 发明名称 |
Taxane Particles and Their Use |
| 摘要 |
Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided. |
| 申请公布号 |
US2016354336(A1) |
申请公布日期 |
2016.12.08 |
| 申请号 |
US201615174505 |
申请日期 |
2016.06.06 |
| 申请人 |
CRITITECH, INC. |
发明人 |
BALTEZOR Michael;FARTHING Joseph;SITTENAUER Jake;ESPINOSA Jahna;CAMPBELL Samuel;MCCLOREY Matthew;FISCHER Julia K.;WILLIAMS Mark D. |
| 分类号 |
A61K31/337;A61K9/16 |
主分类号 |
A61K31/337 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition, comprising particles including at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, wherein the particles have one or both of the following characteristics:
(i) a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or (ii) have a specific surface area (SSA) of at least 18 m2/g. |
| 地址 |
Lawrence KS US |
