NOVEL 2-SACCHARINYLMETHYL ARYL CARBOXYLATES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND COMPOSITIONS AND METHOD OF USE THEREOF

摘要

NOVEL 4-R4-R5-2-SACCHARINYLMETHYL ARYL CARBOXYLATES OF FORMULA I FORMULA 1PREPARED BY REACTING A 4-R4-R5-2-HALOMETHYLSACCHARIN WITH AN ARYLCARBOXYLIC ACID IN THE PRESENCE OF AN ACID-ACCEPTOR, COMPOSITIONS THEREOF AND THEIR USE IN THETREATMENT OF DEGENERATIVE DISEASES ARE DESCRIBED.