| 发明名称 |
Use of phosphono derivatives as anti-malarials |
| 摘要 |
The invention provides the use of phosphono derivatives of selected aliphatic acids represented by the structural formulae R-COOH, R being PO<SUB>3</SUB>H<SUB>2 </SUB>or CR<SUB>1</SUB>R<SUB>2</SUB>-PO<SUB>3</SUB>H<SUB>2 </SUB>where R<SUB>1</SUB>/R<SUB>2 </SUB>are H, OH, COOH or alkyl groups for the treatment of malaria. The use of the compound comprises administering an effective amount of said compounds for in vitro and in vivo studies using malarial parasites (Plasmodium falciparum and Plasmodium berghei).
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| 申请公布号 |
US2005171063(A1) |
申请公布日期 |
2005.08.04 |
| 申请号 |
US20040893474 |
申请日期 |
2004.07.16 |
| 申请人 |
MALHOTRA PAWAN;DASARADHI PALAKODETI V.N.;MOHAMMED ASIF;HOSSAIN MANZAR J.;MUKHERJI SUNIL;MANIVEL VENKATASAMY;SUBBA RAO KANURY V.;SUBRAYAN PARAMESWARAN P.;CHATTERJI ANIL |
发明人 |
MALHOTRA PAWAN;DASARADHI PALAKODETI V.N.;MOHAMMED ASIF;HOSSAIN MANZAR J.;MUKHERJI SUNIL;MANIVEL VENKATASAMY;SUBBA RAO KANURY V.;SUBRAYAN PARAMESWARAN P.;CHATTERJI ANIL |
| 分类号 |
A61K31/315;A61K31/335;A61K31/4745;A61K31/506;A61K31/555;A61K31/66;A61K31/662;A61K33/30;(IPC1-7):A61K31/66;A61K31/474 |
主分类号 |
A61K31/315 |
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