发明名称 |
Methods for designing and preparing vaccines comprising directed sequence polymer compositions via the directed expansion of epitopes |
摘要 |
The instant invention comprises a process of preparing a composition comprising directed sequence polymer (DSP) mixtures that act as epitopes and useful as vaccines, such DSP synthesized according to a set of rules regarding the identity and the frequency of occurrence of amino acids that substitute a base or native amino acid of a known epitope. The resulting composition is a mixture of related peptides for therapeutic use as a vaccine, preferably for infectious agents that are immune evasive. |
申请公布号 |
AU2008311897(B2) |
申请公布日期 |
2015.03.26 |
申请号 |
AU20080311897 |
申请日期 |
2008.10.16 |
申请人 |
PEPTIMMUNE, INC. |
发明人 |
MATHERS, THOMAS;ZANELLI, ERIC;BONNIN, DUSTAN;KRIEGER, JEFF |
分类号 |
C07K1/04;A61K39/145 |
主分类号 |
C07K1/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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