发明名称 |
Molecular Diagnostic Method and Treatment in Dementia With Lewy Bodies |
摘要 |
The present invention describes methods of molecular diagnosis of a concrete form of a-synucleinopathy, the dementia with Lewy bodies (DLB), associated to the levels of ubiquitin carboxy-terminal hydrolase L1 (UCH-1) or the alteration of its ubiquityl-ligase activity. It also refers to the use of compounds that permit the modification of the UCH-L1 levels or of the enzymatic activity of UCH-L1. This invention has application in the diagnosis and treatment of patients suffering from DLB. |
申请公布号 |
US2009028845(A1) |
申请公布日期 |
2009.01.29 |
申请号 |
US20050658057 |
申请日期 |
2005.07.18 |
申请人 |
ORYZON GENOMICS, S.A. |
发明人 |
MAES TAMARA;BUESA ARJOL CARLOS;BARRACHINA CASTILLO MARTA;FERRER ABIZANDA ISIDRO |
分类号 |
A61K39/395;A61K31/7105;C12Q1/00;C12Q1/68;C40B30/00 |
主分类号 |
A61K39/395 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|