Method Of Manufacturing Wettable Silicone Hydrogel Contact Lenses

摘要

A method for manufacturing a silicone hydrogel contact lens is described that comprises curing a polymerizable composition comprising at least one siloxane monomer and at least one hydrophilic vinyl-containing monomer in a contact lens mold comprising a molding surface having a coating comprising a hydrophilic polymer. The hydrophilic coating is not solubilized by the polymerizable composition during the curing step. The resulting polymeric lens body is removed from the mold, washed to remove any of the hydrophilic polymer that may have transferred from the mold surface to the lens during the curing or lens removal process, and packaged to provide a silicone hydrogel contact lens having a contact angle that is lower than what it would otherwise be had the lens been cured in the same contact lens mold lacking the hydrophilic coating.

主权项

1. A method of manufacturing a silicone hydrogel contact lens, said method comprising:
a. curing a polymerizable composition comprising at least one siloxane monomer and at least one hydrophilic vinyl-containing monomer in a contact lens mold to form a polymeric lens body; and b. washing and packaging the polymeric lens body to provide a silicone hydrogel contact lens having a first contact angle; wherein said contact lens mold comprises a molding surface coated with a hydrophilic coating comprising at least one hydrophilic polymer, wherein the hydrophilic coating is not solubilized by the polymerizable composition during the curing step, and the silicone hydrogel contact lens is substantially free of the hydrophilic polymer from the hydrophilic coating, and the first contact angle is lower than a second contact angle of a control silicone hydrogel contact lens cured in an uncoated, but otherwise identical, contact lens mold and manufactured using a method that is identical to the method of manufacturing the silicone hydrogel contact lens.