| 发明名称 |
COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITY |
| 摘要 |
Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors described herein. |
| 申请公布号 |
WO2016168472(A1) |
申请公布日期 |
2016.10.20 |
| 申请号 |
WO2016US27549 |
申请日期 |
2016.04.14 |
| 申请人 |
CASE WESTERN RESERVE UNIVERSITY;BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
MARKOWITZ, Sanford D.;READY, Joseph;ZHANG, Yongyou;ANTCZAK, Monika;WILLSON, James K.V.;POSNER, Bruce A.;GREENLEE, William |
| 分类号 |
A61K31/4365;C07D333/10;C07D495/04 |
主分类号 |
A61K31/4365 |
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