发明名称 |
COMPOSITION FOR PREVENTION OR TREATMENT OF BRONCHIAL ASTHMA COMPRISING PKR INHIBITOR AS ACTIVE INGREDIENT |
摘要 |
The present invention relates to a composition for prevention or treatment of bronchial asthma comprising a PKR inhibitor as an active ingredient. The PKR inhibitor and derivatives thereof according to the present invention can be used as a pharmaceutical for prevention, amelioration or treatment of bronchial asthma and as a supplementary health food because the PKR inhibitor and derivatives thereof reduce the total counts of inflammatory cells, eosinophils, neutrophils and lymphocytes in bronchoalveolar lavage fluid of neutrophilic severe asthma-induced mice, reduce airway inflammation and airway hyper-responsiveness, and reduce inflammatory mediators. |
申请公布号 |
WO2016129802(A2) |
申请公布日期 |
2016.08.18 |
申请号 |
WO2015KR13791 |
申请日期 |
2015.12.16 |
申请人 |
INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY;CHONBUK NATIONAL UNIVERSITY HOSPITAL |
发明人 |
LEE, Yong Chul;KIM, So Ri |
分类号 |
A61K31/428;A61K31/4178;A61K31/429 |
主分类号 |
A61K31/428 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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