| 主权项 |
1. A valve prosthesis comprising:
an expandable frame comprising an outflow portion and an inflow portion connected to the outflow portion, the frame having a longitudinal axis and defining a central lumen extending between the outflow portion and the inflow portion, wherein the frame is generally cylindrical in a fully expanded configuration, wherein, when the frame is in a fully expanded configuration, (i) an outer surface of the inflow portion is concave, (ii) the inflow portion has an upper inflow portion defining an upper edge, a lower inflow portion defining a lower edge, and a waist between the upper edge and the lower edge, (iii) the upper inflow portion flares outwardly from the longitudinal axis and the central lumen of the frame to greater extent than the lower inflow portion, (iv) a transverse distance from the upper inflow portion to the longitudinal axis of the frame continuously increases from the waist to the upper edge, and (v) a transverse distance from the lower inflow portion to the longitudinal axis of the frame continuously increases from the waist to the lower edge. |
