PROCESS FOR PRODUCTION OF PHENOL DERIVATIVES SUBSTITUTED WITH IODINE AT ORTHO POSITION

摘要

[PROBLEMS] To provide a process for producing 2-iodophenol derivatives or 2,6-diiodophenol derivatives by iodinating phenol derivatives at ortho position which can dispense the recovery of iodine and makes it possible to produce the objective iodinated derivatives at low cost, in high yield, and with high quality. [MEANS FOR SOLVING PROBLEMS] High-quality 2-iodophenol derivatives or 2,6-diiodophenol derivatives can be obtained in high yield by reacting a phenol derivative with molecular iodine in the presence of a pyridine and either hydrogen peroxide or iodic acid as oxidizing agent through efficient iodination with a nearly theoretical amount of iodine based on the starting phenol derivative.